"According to the Centers for Disease Control (CDC), 61 million Americans — 25 percent of the population — currently suffer from cardiovascular disease (CVD). The term cardiovascular disease covers a broad spectrum of disorders that include high blood pressure, coronary heart disease (heart attack and chest pain), stroke, birth defects of the heart and blood vessels, and congestive heart failure.
Reducing serum cholesterol levels — especially the low-density (LDL) fraction — is a well-established, effective strategy for preventing cardiovascular disease and reducing coronary events and mortality. Unfortunately a recent report in the journal Circulation found that between 1988 and 2000 average total serum cholesterol concentrations in the US population declined by a mere 1%. And while 91% of respondents to a survey conducted by the American Heart Association felt it was ""important to them personally to have a healthy cholesterol level,"" fewer than 50% knew their own cholesterol level, and 53% either didn’t know, or overestimated, the recommended cholesterol level for a healthy adult.
Sytrinol has polymethoxylated flavones (PMFs) that decrease apoprotein B, a structural protein needed for endogenous synthesis of LDL cholesterol. PMFs (tangeritin and nobiletin) decrease diacylglycerol acetyl transferase, a liver enzyme needed for endogenous synthesis of triblycerides. More human studies are needed with Sytrinol to determine if this product is a helpful addition to healthy cholesterol management."
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